Goals from Eddie Hutchinson and Tony Rougier give The Bees their first points of the season.
Wally Downes gave Ben May his debut in 4-4-2 formation. Leo Roget could not play through injury so Lee Fieldwick stepped in at left-back with Matt Somner at centre-back.
Michael Dobson was finding his range on crosses very quickly, a Jay Smith flick from a free-kick gave the captain a chance to score but Les Pogliacomi saw the ball at the last second to palm it round the post. Oldham took the lead against the run of play in the sixteenth minute. In a mirror image of Saturday's defeat at Wrexham, a poorly marked header from allowed Dean Holden to score.
Brentford levelled things before half-time to the relief of the Griffin Park
crowd, Eddie Hutchinson bravely flung himself at a Dobson left-wing cross into a body of players. The end product was The Bees' first goal from open play for 401 minutes. Hutchinson left the field momentarily to receive treatment for a head wound.
Brentford escaped a minute into the second half after David Ayres twenty-yard shot hit the post. Eddie Hutchinson again was the provider for Tony Rougier, but Pogliacomi parried his shot. Sixty seconds later, John Eyre hit the bar for Oldham. In the fifty-seventh minute, Brentford clinched the three points. Tony Rougier latched into Paul Smith's long goal kick to spin on a sixpence to volley home.
In the 64th minute, further drama was to follow as Ibrahima Sonko conceded a penalty. Paul Smith was equal to David Ayres spot-kick, diving to his right to give Wally Downes a perfect leaving present before he sit outs a three-match suspension.
Referee Williamson blew for full-time in front of a relieved Griffin Park
as Brentford hung on to record their first victory of the season.